CD Bioparticles Introduces Innovative Range of Functional Polystyrene Particles
- 28-Nov-2023 1:40 PM
- Journalist: Kim Chul Son
CD Bioparticles has unveiled an extensive array of new Functional Polystyrene Particles, featuring diverse surface functional groups, including amino, carboxyl, and hydroxyl groups. Drawing upon its extensive experience in the pharmaceutical and life science domains, the company's latest offering showcases versatility for applications in immunoassays, analytical chemistry, and bio-nano interactions research.
These Functional Polystyrene Particles exhibit not only the inherent properties of polymer microspheres, such as impeccable sphericity, a substantial specific surface area, excellent surface activity, and consistent, controllable particle size, but also unique characteristics like high rigidity, insolubility in common solvents, and resistance to easy biodegradation. The benzene ring within these polystyrene microspheres imparts robust reactivity, enabling a series of functionalization reactions that introduce various active functional groups to the microsphere surface, thereby optimizing the properties of polystyrene.
In the realm of diagnostic and bioseparation applications, polystyrene particles serve as a flexible platform. Attachment of biological ligands to these particles can be achieved through diverse methods, including adsorption onto plain polystyrene particles, covalent adsorption onto surface-functionalized particles, and attachment of ligands onto particles precoated with binding proteins such as streptavidin, protein A, or protein G.
CD Bioparticles now offers an assortment of functional polystyrene particles, each endowed with distinct surface functional groups. Examples include particles designed with Acrylate surface and supplied in water, those with Alkyl-OH surface coatings to significantly reduce nonspecific protein binding, particles with surface Amine groups, and Amine PS/DVB Particles. Additionally, particles functionalized with COOH groups on the surface, such as Carboxyl Porous PS/DVB Particles cross-linked with 0.5% DVB, are available.
These newly introduced functionalized polystyrene particles find application across various domains, such as organic synthesis, analytical chemistry, drug delivery materials, bioimaging, labeling, and immunoassays. Noteworthy features include outstanding stability, high binding capacity, ultra-high specificity (low background), and extensive validation in both academic and industrial-scale immunoturbidimetric assays.
For instance, the DiagPoly™ Amine Polystyrene Particles, 0.025 μm (Cat. No. DFO-L026), are specifically functionalized with amine groups (NH2) on the surface, facilitating covalent attachment of proteins, peptides, and nucleic acids. These particles serve multiple purposes, acting as standards or markers, participating in immunoassays such as latex agglutination assays and solid-phase enzyme immunoassays, or being coated with proteins for deployment in research and diagnostic tests.
Beyond the scope of carboxyl and amino functionalized particles, CD Bioparticles extends its offerings to larger functionalized particles and diverse surface chemicals, including epoxy, PEG, NHS, and cycloalkane click chemicals. This comprehensive suite of Functional Polystyrene Particles reflects CD Bioparticles' commitment to advancing research and development across various scientific domains, providing scientists and researchers with cutting-edge tools for their investigations.