U.S. Rifaximin Prices to Trend Upward in September on Supply and Inflation Factors

U.S. Rifaximin Prices to Trend Upward in September on Supply and Inflation Factors

Peter Schmidt 22-Sep-2025

In September 2025, U.S. Rifaximin prices are expected to rise gradually following August’s stability. Steady increases are most probable because possible delays in the supply chain from China's Golden Week, prodded higher freight charges, and ongoing U.S. inflation. Purchasers can deliberately front-load buying to account for delays, but total demand is expected to be stable. Prices must increase steadily, but acceptably, in Rifaximin during September, establishing the pattern for steady growth into Q4 2025.

Key Highlights

  • U.S. Rifaximin prices remained largely stable in August 2025, with a marginal gain of +0.07%.
  • Demand for Rifaximin remains steady, driven by its critical use in treating hepatic encephalopathy and other gastrointestinal conditions.
  • Potential supply disruptions from China’s Golden Week holiday could exert modest upward pressure on prices.
  • Buyers may cautiously increase Rifaximin procurement to mitigate risk of delays.
  • Inflationary pressures in the U.S. continue to affect pharmaceutical supply chain costs.

U.S. Rifaximin prices changed little in August 2025, recording a small +0.07% increase. This small movement is indicative of firm demand for the Rifaximin as a function of stable treatment demand. Buyers remained cautious in their buying, with no overbidding, because overall supply conditions still proved to be sufficient to meet underlying requirements.

In entering September, Rifaximin prices are expected to trace a moderate upward trend, if at a slower pace. Among the underlying global factors supporting this trend is the impending Chinese Golden Week holiday, opening early in October. During this period, many Chinese manufacturers and exporters downscale or halt operations temporarily, and this might limit export flows and generate minor shipping delays. U.S. drug importers like Rifaximin, which are pharmaceutical intermediates, might end up paying slightly higher freight for this, and this will get passed on to the local market.

The US consumers likely react with cautious buying in September. With total consumption of Rifaximin being stable, there will be a moderate level of pre-buying to anticipate probable supply constraints and higher shipping cost. Such rationale stockpiling could add incrementally to the modest price increase in the month.

Broader macroeconomic factors are also influencing pricing. U.S. inflation continues to apply upward pressure on operational and logistics costs across the pharmaceutical sector. Even with balanced demand, these cost-side pressures are slowly embedding into the pricing of essential medicines, including Rifaximin, reinforcing the gradual upward trend.

Factors Driving September Price Movements

The anticipated modest increase in Rifaximin prices during September 2025 owes it to a combination of cost-side pressures. Limited shipping availability, possible export hiccups during Golden Week of China, and sustained inflation are making American buyers pre-fund some purchasing. The combined pressures will most likely stand to foster a gradual build-up in prices. 

Outlook for Q4 2025

In the fourth quarter of 2025, Rifaximin prices are projected to be gradually increasing. Experts say that extrinsic factors like global freight volatilities, short-term export disruptions, and sustained inflation will impact prices, while the underlying medical demand for the drug is stable. Overall, the trend is expected to be gradual, with smooth, manageable rises and not sharp fluctuations.

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Rifaximin

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