For the Quarter Ending December 2025
Bupropion Prices in North America
- In United States, the Bupropion Price Index inched up quarter-over-quarter in Q4 2025, influenced by rising consumer prices.
- Bupropion production costs faced upward pressure as PPI increased 3.0% year-over-year in November 2025.
- Bupropion demand outlook remained strong, supported by a 3.3% year-over-year increase in retail sales in November 2025.
- Organic chemical intermediate costs and US Henry Hub natural gas spot prices faced downward pressure in Q4 2025.
- The unemployment rate of 4.4% in December 2025 indicated a strong labor market, supporting healthcare access.
- Industrial production increased 2.0% year-over-year in December 2025, despite manufacturing output declining in Q4 2025.
- US pharmaceutical preparations imports decreased in October 2025, impacting overall Bupropion supply dynamics.
- Tighter capital and higher financing costs impacted the chemical industry in Q4 2025, affecting Bupropion.
Why did the price of Bupropion change in December 2025 in North America?
- Producer Price Index increased 3.0% year-over-year in November 2025, raising Bupropion manufacturing input costs.
- Retail sales increased 3.3% year-over-year in November 2025, indicating robust consumer spending supporting healthcare.
- Organic chemical intermediate costs faced downward pressure through the end of 2025, influencing Bupropion production.
Bupropion Prices in APAC
- In China, the Bupropion Price Index rose quarter-over-quarter in Q4 2025, influenced by an upward trend in manufacturing input costs.
- Bupropion production costs trended upward in Q4 2025, despite producer prices declining 1.9% year-over-year in December 2025.
- Weak consumer spending, with retail sales growing 0.9% and CPI at 0.8% in December 2025, affected Bupropion demand.
- A 5.1% unemployment rate in December 2025 indicated reduced disposable income, indirectly affecting Bupropion demand.
- China's pharmaceutical sector thrived in 2025, bolstering Bupropion demand despite moderated overall economic growth in Q4 2025.
- Manufacturing sector expanded in December 2025, industrial production grew 5.2% year-over-year, supporting supply chains.
- China's medicine exports, including chemical active pharmaceutical ingredients, steadily increased in the first 11 months of 2025.
- Raw materials inventory declined in November 2025, but companies reported sufficient inventories in December 2025.
Why did the price of Bupropion change in December 2025 in APAC?
- Manufacturing input costs accelerated in December 2025, pressuring Bupropion production expenses upward.
- Weak consumer spending, with retail sales growing 0.9% year-over-year in December 2025, tempered Bupropion demand.
- Producer prices declined 1.9% year-over-year in December 2025, indicating lower overall input costs.
Bupropion Prices in Europe
- In Germany, the Bupropion Price Index fell quarter-over-quarter in Q4 2025, influenced by reduced producer costs in December 2025.
- Bupropion production costs decreased in Q4 2025, as the Producer Price Index declined by 2.5% year-over-year in December 2025.
- Bupropion demand remained stable in Q4 2025, supported by consistent German pharmaceutical demand for high-value therapies.
- Bromine feedstock costs for Bupropion production in Europe inched down in November 2025.
- European industrial natural gas prices remained elevated in Q4 2025, impacting manufacturing expenses.
- The Manufacturing Index contracted in December 2025, indicating a slowdown in Germany's economic activity.
- Consumer confidence deteriorated to -17.5 in December 2025, dampening discretionary health spending.
- German industrial production inched up by 0.8% year-over-year in October 2025, despite overall contraction.
- Unemployment at 6.2% and CPI at 1.8% in December 2025 impacted consumer purchasing power.
Why did the price of Bupropion change in December 2025 in Europe?
- Producer Price Index declined by 2.5% year-over-year in December 2025, reducing manufacturing input costs.
- Bromine feedstock costs in Europe inched down in November 2025, lowering Bupropion production expenses.
- Contracting Manufacturing Index in December 2025 signaled weaker industrial activity and dampened demand.
For the Quarter Ending September 2025
Bupropio Prices in North America
- In United States, Bupropion Price Index rose in Q3 2025, driven by rising production costs.
- Bupropion production costs increased in Q3 2025, influenced by 2.6% PPI rise in August 2025.
- Bupropion demand supported by 5.42% retail sales increase and 4.3% unemployment in September 2025.
- Bupropion demand faced headwinds from 3.0% CPI increase and declining consumer confidence in September 2025.
- US manufacturing inventories tightened in Q3 2025; chemical inventories shrank due to destocking.
- US chemical manufacturing output contracted in Q3 2025; nondurable goods production slipped in September.
- Bupropion Price Forecast indicates upward pressure from sustained pharmaceutical intermediate demand and rising costs.
- Trade tensions and U.S. tariffs on imported chemicals impacted the market in Q3 2025, affecting supply.
- Strengthened US pharmaceutical market sentiment and drug approvals in Q3 2025 supported generic demand.
Why did the price of Bupropion change in September 2025 in North America?
- Bupropion input costs increased in Q3 2025, driven by 2.6% PPI rise in August.
- US manufacturing and chemical inventories tightened in Q3 2025, limiting Bupropion supply.
- Strong retail sales (up 5.42% in September 2025) supported Bupropion demand.
Bupropio Prices in APAC
- In China, the Bupropion Price Index remained stable in Q3 2025, influenced by mixed macroeconomic signals.
- Bupropion production costs declined in Q3 2025, as PPI fell by 2.3% in September 2025, reducing factory-gate prices.
- Bupropion demand outlook was tempered by pessimistic consumer confidence, recorded at 89.6 in September 2025.
- The Pharmaceutical API market expanded in 2025, providing underlying support for Bupropion demand.
- Industrial production rose by 6.5% in September 2025, bolstering supply chain stability for Bupropion manufacturing.
- Retail sales grew by 3.0% in September 2025, indicating stable consumer spending power for medications.
- Persistent overcapacity in China's chemical industry during Q3 2025 influenced Bupropion supply and inventory.
- Natural gas prices stabilized in Q3 2025, contributing to stable energy costs for Bupropion production.
- The Manufacturing Index contracted in September 2025, signaling a broader slowdown affecting Bupropion's supply chain.
Why did the price of Bupropion change in September 2025 in APAC?
- Falling PPI (-2.3% in September 2025) reduced production costs, influencing Bupropion pricing.
- Pessimistic consumer confidence (89.6 in September 2025) tempered demand, impacting Bupropion price stability.
- Persistent chemical overcapacity in Q3 2025 contributed to ample supply, pressuring Bupropion prices.
Bupropio Prices in Europe
- In Germany, the Bupropion Price Index remained stable quarter-over-quarter in Q3 2025, reflecting balanced market dynamics.
- Bupropion production costs faced upward pressure from a 2.4% CPI in September 2025, increasing operational expenses.
- Conversely, a -1.7% PPI in September 2025 indicated lower producer input costs, easing Bupropion manufacturing expenses.
- The Bupropion demand outlook was supported by a low 3.9% unemployment rate in September 2025, bolstering consumer affordability.
- However, consumer confidence declined significantly by -23.6 index points in September 2025, posing a bearish demand outlook.
- High energy and raw material costs continued to burden the German chemical industry throughout Q3 2025, affecting Bupropion production.
- The Manufacturing Index contracting in September 2025, alongside a -1.0% industrial production decline, signaled broader economic slowdown.
- Bupropion price forecast suggests continued stability, as resilient pharmaceutical output balances general industrial weakness in Q3 2025.
Why did the price of Bupropion change in September 2025 in Europe?
- A -1.7% PPI in September 2025 indicated lower producer input costs, easing Bupropion production.
- High energy costs and a 2.4% CPI in September 2025 increased Bupropion operational burdens.
- Strong consumer affordability from a 3.9% unemployment rate balanced weak consumer confidence.
For the Quarter Ending December 2022
North America
North American region, primarily the United States market, displayed descending pricing sentiments for Bupropion throughout the final Quarter of 2022. At the start of the fourth quarter, the prices remained on the stable side as the demand remained dormant, following the trend of the previous month.
Market players continue to keep a close eye on various factors that have impacted the market of almost all commodities, including Bupropion. Till November, the prices remained sturdy, with moderate demand balanced with overall supplies within the domestic market. Following December, the cost of Bupropion declined considerably and got settled at USD 71850/ MT CFR Los Angeles.
Asia Pacific
The prices of Bupropion in the Asia Pacific region, majorly in China, demonstrated a significant dip with ending of the last Quarter of 2022. Government data showed the official manufacturing purchasing managers index (PMI) fell to 48.0 in November, slipping well below last month's reading of 49.2 as steadily rising COVID-19 cases in the fourth quarter caused further disruptions and the prices of all the commodities, including Bupropion. Due to restrictions on the export of all commodities, including Bupropion, China's main issue was managing congested logistics on the key trade channels to North America and Europe during November, which additionally affected the price trends of Bupropion. With the end of the fourth quarter of 2022, the prices of Bupropion got assembled at USD 71000/MT FOB Shanghai, with declining demand and stockpiling of inventories among the market players.
Europe
During the fourth quarter of 2022, the prices of Bupropion showed mixed market sentiments in the European region. October month witnessed a continuous decrement in end-user demand for Bupropion. Following November, the prices inclined considerably and got stable in December with the settlement of USD 75570/MT CFR Hamburg in Germany. Furthermore, Bupropion's price trend in Germany was supported by a rapid decline in supply chain interruption and shipping costs. However, as growing energy prices began to level down at the end of 2022, inflation in Europe declined in December for the second consecutive month. Due to a decline in international orders, notably from exporting nations like China, demand decreased from the previous month. However, the inventories, with market players', remained larger, and their inquiries weaker during the Thanksgiving break.
For the Quarter Ending September 2022
North America
The market trend for Bupropion experienced a declining price trajectory during the third Quarter of 2022, backed by weakened downstream demand in the domestic market. Furthermore, Bupropion was an Active Pharmaceutical Ingredients (API) whose imports into the US were severely affected due to China's zero-covid policy and worsened climatic conditions admitted to the hurricane. Also, various Chinese production activities were forced to shut down in the second half of Q3 due to the heat wave and a power constraint, which negatively affected US imports. Moreover, towards the termination of Q3, the prices witnessed a continuous decrease and settled at USD 185000/MT CFR Los Angeles.
APAC
In the APAC region, during the third quarter of 2022, the prices of Bupropion witnessed a fluctuating trend owing to variable downstream demand and the supply side. In the first half of q3, the prices rose significantly, leading to the shortage of stocks with the suppliers, which in turn propelled them to increase their quotation rates. Additionally, disrupted trading activities leading to delayed shipments and climatic variations were another factor that supported the market sentiments of Bupropion in the region. Furthermore, towards the termination of q3, the prices decreased considerably, backed by weaker demand and enough supplies, with the settlement of USD 176000 /MT FOB Shanghai.
Europe
The European region witnessed a similar market sentiment in the prices for Bupropion as the APAC region, owing to healthy downstream demand in the market during h1 of q3. Across Europe, rising energy costs due to the Russia-Ukraine conflict and the rerouting activities kept the market on a higher note. Additionally, delayed exports from China due to Covid restrictions and halted transportation resulted in low inventories in the regional market till the mid of q3. Towards the termination of q3, the prices for Bupropion dropped significantly owing to decremented demand for sufficient supplies with adequate suppliers. The prices witnessed in September for Bupropion settled at USD 200000 /MT CFR Hamburg.
For the Quarter Ending June 2022
North America
The North American region witnessed a declining pricing sentiment throughout the second quarter of 2022, backed by weaken offtake and sufficient inventories in the market. Furthermore, the prices went low owing to the consistent availability of Upstream feed Bromine and in-sufficient downstream demand from the market. Moreover, lessen queries from the Chinese market due to the C0VID-19 lockdown restriction and higher inflation pressure amid war led to a price decrement of Bupropion in US. The prices recorded at the end of second quarter was at USD 189000/MT CFR Houston with a declination of 0.34 percent. Additionally, fluctuating in the supply-demand gap throughout the second quarter kept the market sentiments of Bupropion on a weaker side.
Asia Pacific
During the second quarter, the prices of Bupropion witnessed an incremented state in the APAC region. Strong downstream demand was seen in Q2 with heightened prices of Bupropion. Consistent offtake and limited availability from end-user industries impacted the price trends of Bupropion. At the onset of Q2, the prices decreased due to the covid-restriction and affected production rate in the Chinese market admits deterred demand. Moreover, despite declining feedstock Bromine prices, the market price trend for Bupropion remained at a higher state owing to its surging demand and enough feedstock inventories to meet its demand. Further, with the end of April 2022, the prices surged consistently at a higher rate recorded at USD 181000/MT FOB Shanghai in the Chinese market.
Europe
The European market witnessed an Upward pricing trajectory with the settlement of USD 206000/MT CFR Hamburg during the second quarter of 2022 due to strong demand from end-user enterprises and a higher inflation rate. Furthermore, the supply disruption leading to the shortage of production activities and stock caused the traders and sellers in the region to offer the products at a reduced price to spot buyers. Increasing Russian-Ukraine geopolitical tension and rerouting transporting activities impacted the price trends of Bupropion in the European Region. Moreover, higher energy value results in uptrend pressure on input cost of feed Bromine resulting in the price enhancement of Bupropion further in the overall region.
