For the Quarter Ending September 2025
North America
• In United States, the Domperidone Price Index fell quarter-over-quarter in Q3 2025, driven by deteriorating customer market demand.
• Domperidone production costs increased due to a 2.6 percent rise in the Producer Price Index in August 2025.
• Overall industrial production in the United States inched up by only 0.1 percent year-over-year in September 2025.
• The Consumer Price Index increased 3.0 percent year-over-year in September 2025, impacting overall production expenses.
• Demand for chemicals deteriorated in Q3 2025, with new orders declining in both domestic and foreign markets.
• US natural gas prices saw an uptick in Q3 2025, though easing in September, affecting energy feedstock costs.
• Chemical industry inventories experienced accelerated destocking during Q3 2025, indicating efforts to reduce stock levels.
• U.S. chemical imports from China experienced a steep decline in July 2025, impacting regional supply dynamics.
• The unemployment rate was 4.3 percent in September 2025, supporting consumer spending and healthcare affordability.
Why did the price of Domperidone change in September 2025 in North America?
• Weak customer market demand for chemicals persisted, leading to declining new orders in Q3 2025.
• Producer Price Index rose 2.6 percent in August 2025, increasing input costs for Domperidone manufacturing.
• Chemical production levels declined in Q3 2025, tightening regional supply due to maintenance turnarounds.
Europe
• In Germany, the Domperidone Price Index remained stable in Q3 2025, influenced by contracting manufacturing activity.
• Domperidone production costs remained elevated in Q3 2025, despite a -1.7% PPI decline in September 2025.
• European natural gas prices softened in July and August 2025, then trended upward in September 2025.
• German electricity prices strengthened in July 2025 and fluctuated in September 2025, raising input costs.
• Demand for generic Domperidone in Germany saw broad market access during Q3 2025 due to lower costs.
• Overall German industrial production declined by -1.0% year-over-year in September 2025, dampening demand.
• Consumer confidence in Germany declined to -23.6 in September 2025, impacting discretionary spending.
• A 2.4% CPI in September 2025 indicated moderate inflation, increasing operational costs for Domperidone producers.
• German chemical and pharmaceutical production declined in Q3 2025, with capacity utilization below profitability.
Why did the price of Domperidone change in September 2025 in Europe?
• Contracting manufacturing activity in September 2025, indicated by the Manufacturing Index, dampened demand.
• High input costs persisted in Q3 2025, despite a -1.7% PPI decline in September 2025.
• Weak consumer confidence, at -23.6 in September 2025, reduced demand for OTC Domperidone.
APAC
• In China, the Domperidone Price Index fell quarter-over-quarter in Q3 2025, driven by deflationary pressures.
• Domperidone production costs declined in Q3 2025, influenced by depressed ethylene feedstock and a slight dip in benzene in August.
• Pharmaceutical raw material demand strengthened in 2025, despite China's Manufacturing Index contracting in September 2025.
• Industrial production increased by 6.5% year-on-year in September 2025, supporting a favorable economic environment.
• Retail sales grew by 3.0% year-on-year in September 2025, bolstering consumer demand for over-the-counter products.
• New U.S. tariffs on pharmaceutical imports from China in July 2025 increased costs, impacting Domperidone trade flows.
• Ample ethylene inventories and rising global oil inventories in Q3 2025 contributed to downward pressure on feedstock.
• China's chemical overcapacity in Q3 2025, alongside self-sufficiency goals, exerted pressure on Domperidone markets.
Why did the price of Domperidone change in September 2025 in APAC?
• Deflationary pressures, with CPI at -0.3% year-on-year in September 2025, reduced overall pricing power.
• Production costs declined due to a -2.3% year-on-year PPI in September 2025 and depressed ethylene feedstock.
• Weak overall chemical demand in Q3 2025, despite positive retail sales, limited Domperidone price increases.
For the Quarter Ending December 2022
North America
This product is discontinued in this region.
APAC
Domperidone API witnessed a mixed pricing sentiments trend throughout the fourth quarter of 2022 in the Asia Pacific region. The prices declined consistently during October, followed by the trend of September owing to reduced demand which compelled the local merchants to decrease their domestic prices. Following November, the demand surged gradually, which was balanced by overall inventories resulting from the distributors within the domestic market. Later in December, a surge in COVID-19 cases affected the supplies and end-user demand, which led to piled-up stocks of Domperidone. Overall, the price of Domperidone noted at the end of the fourth quarter was assembled at USD 107700/MT FOB Shanghai in China.
Europe
This product is discontinued in this region.
For the Quarter Ending September 2022
North America
This product is discontinued in this region.
Asia Pacific
APAC region witnessed decreasing price trajectory of Domperidone API during the third quarter of 2022, backed by reduced downstream demand from the end-user pharmaceutical sector. Furthermore, weak customer inquiries and reduced demand with sufficient inventories supported the price trends of Domperidone API in the market. Additionally, in the mid of Q3, the prices followed similar market sentiments in an upward direction. Towards the termination of Q3, the prices for Domperidone API witnessed were assessed at INR 3182000/MT Ex Hyderabad with a slight decremented trend.
Europe
This product is discontinued in this region.
For the Quarter Ending in June 2022
North America
This product is discontinued in this region.
Asia Pacific
In APAC, the domperidone API price increased in the Second Quarter of 2022. Offtake from various downstream sectors, including pharmaceutical and biopharmaceutical sectors, was one of the important factors driving the domperidone API price. India, the leading exporter of Domperidone API to this market, saw a spike in its prices during the second quarter due to transport cost disruptions amid cargo shortages and re-routing of transport vehicles. In addition, supply disruptions and labor shortages due to increased downstream demand have increased the price of Domperidone API in the regional market. Also, at the end of Q2 in India, API Domperidone price stood at INR 4120000/MT Ex-Hyderabad.
Europe
This product is discontinued in this region.
