For the Quarter Ending September 2025
North America
• In the United States, the Fluconazole Price Index rose quarter-over-quarter in Q3 2025, driven by escalating production costs.
• Fluconazole production costs increased due to a 2.6% year-over-year rise in PPI in August 2025, impacting raw materials.
• Benzene prices showed upward momentum throughout Q3 2025, contributing to higher Fluconazole feedstock expenses.
• Natural gas prices strengthened in Q3 2025, increasing energy and operational costs for Fluconazole manufacturing.
• Fluconazole demand was supported by a 5.42% year-over-year increase in retail sales in September 2025.
• A low unemployment rate of 4.3% in September 2025 enhanced consumer access to healthcare, boosting Fluconazole demand.
• Chemical industry inventories shrank in Q3 2025, and US chemical production contracted, tightening Fluconazole supply.
• The Fluconazole Price Index faced upward pressure from a 3.0% year-over-year CPI increase in September 2025.
Why did the price of Fluconazole change in September 2025 in North America?
• Rising producer-level inflation (PPI up 2.6% in August 2025) directly increased Fluconazole raw material costs.
• Tightening regional supply resulted from contracted US chemical production and shrinking inventories in Q3 2025.
• Strengthening natural gas prices in Q3 2025 elevated energy and operational expenses for Fluconazole manufacturing.
APAC
• In China, Fluconazole Price Index fell in Q3 2025, due to contracting manufacturing and softened feedstock costs.
• Fluconazole production costs declined in Q3 2025, driven by eased benzene, propylene, and naphtha prices.
• Demand outlook faced headwinds from weakened consumer confidence (89.6 Sept 2025) and pharmaceutical manufacturing pressure.
• China experienced deflationary pressures with CPI decreasing 0.3% and PPI decreasing 2.3% YoY in September 2025.
• The Manufacturing Index contracted in September 2025, reflecting a slowdown impacting supply chain stability.
• Industrial production expanded 6.5% YoY, while retail sales grew 3.0% YoY in September 2025, supporting economic activity.
• A stable unemployment rate of 5.2% in September 2025 supported consistent consumer income and workforce.
• Persistent global overcapacity in chemical building blocks and high benzene inventories impacted Q3 2025.
• Fluconazole price forecast suggests continued pressure due to overcapacity and cautious consumer spending trends.
Why did the price of Fluconazole change in September 2025 in APAC?
• Producer Price Index decreased 2.3% YoY, lowering pharmaceutical production input costs.
• Weakened consumer confidence (89.6 Sept 2025) impacted end-use demand.
• Manufacturing Index contracted in September 2025, reflecting economic weakness and supply.
Europe
• In Germany, Fluconazole Price Index remained stable in Q3 2025, influenced by mixed market signals.
• Fluconazole production costs faced upward pressure in Q3 2025, with CPI rising 2.4% in September 2025.
• Demand for Fluconazole showed resilience in Q3 2025, supported by increased German pharmaceutical production in July 2025.
• Fluconazole Price Forecast suggests stability, balancing Q3 2025 costs against declining producer prices (-1.7% PPI).
• German industrial production declined 1.0% year-over-year in September 2025, impacting raw material availability.
• The Manufacturing Index indicated contracting activity in September 2025, signaling supply chain disruptions.
• Elevated natural gas prices, driven by surging European LNG imports in Q1-Q3 2025, impacted feedstock costs.
• Consumer confidence remained significantly negative (-23.6 index) in September 2025, dampening healthcare spending.
• A low unemployment rate of 3.9% in September 2025 supported Fluconazole demand, enhancing healthcare affordability.
Why did the price of Fluconazole change in September 2025 in Europe?
• Producer prices for chemicals and pharmaceuticals declined slightly in Q3 2025, easing cost pressures.
• German pharmaceutical production increased significantly in July 2025, supporting Fluconazole supply.
• Elevated energy and raw material costs in Q3 2025 pressured Fluconazole production expenses upward.
For the Quarter Ending December 2022
North America
In the fourth quarter of 2022, the Fluconazole market in the North American region showcased an irregular trajectory. It was projected at the start of Q4 2022 that prices would rise in the second month of the quarter due to increasing end-user sector demand and other logistical challenges.
The implementation of zero covid rules hampered trading activity and halted shipments, which benefited the Fluconazole market. The market remained competitive despite higher manufacturing costs brought on by rising energy prices.
However, later in December, as a result of domestic retailers having an adequate supply on hand, fluconazole API prices did decrease. Because of the policies being loosened and the weak downstream demand, the market remained depressed. By the end of Q3 2022, prices were recorded to drop, with values accessed at USD 159020/MT with an average quarterly inclination of 0.99%.
Asia
Fluconazole sales in the Asia Pacific Region had an erratic fourth-quarter trajectory in 2022. It was indicated at the beginning of Q4 2022 that due to rising end-user sector demand and various logistical issues, prices would increase during the second month of the quarter. The adoption of zero covid regulations disrupted shipments and hindered trading activity, which had a favorable impact on the Fluconazole market. Due to increased manufacturing costs driven by rising energy prices, the market remained competitive. Later in December, though, fluconazole API prices did drop because domestic stores had enough inventory on hand. The market remained poor as a result of the relaxing of policies as well as the lackluster downstream demand. Towards the end of Q4, the prices of Salicylic acid were recorded at USD 153200/ton FOB Shanghai (China), with an average quarterly inclination of 0.54%.
Europe
In the third quarter of 2022, Fluconazole API market sentiments in Europe showcased fluctuating behaviour. At the start of Q4 2022 that prices rose till the second month of the quarter as a result of increasing end-user sector demand and other logistical challenges. The implementation of zero covid rules hampered trading activity and halted shipments, which benefited the fluconazole market in the European region. The market remained competitive despite higher manufacturing costs brought on by rising energy prices. However, later in December, because of domestic retailers having an adequate supply on hand, fluconazole API prices did decrease. Also, policies being loosened and the weak downstream demand, the market remained depressed in December. Toward the end of Q4, the values accessed at USD 162020/MT with an average quarterly inclination of 0.67%.
For the Quarter Ending September 2022
North America
In the third quarter of 2022, Fluconazole showcased decelerating price movement in the North American market because of the stabilization in the prices of feed Methanol from the regional market. Throughout the quarter, feed Methanol prices showcased a stable trajectory globally, propelling the prices of Fluconazole to decrease in the regional market. Substantial cost depreciation also affected the price of Flucoazole API. Stable costs for production and regular operational rates ket the market sentiments feeble. By the end of Q3 2022, prices were recorded to drop with values accessed at USD 154450/MT with an average quarterly declination of 0.95%.
Asia
During the third quarter of 2022, the Fluconazole API market witnessed an upward trajectory due to increasing feed prices and fluctuating demand from downstream pharmaceutical industries. With the commencement of Q3 2022, the prices of feed methanol hiked up, affecting the prices of Fluconazole in the domestic market in the Chinese provinces. Additionally, the production halts and lower operational costs prompted by adverse weather conditions further acted the prices to soar continuously. Also, the increased energy price and energy crisis assisted in the hiked-up trajectory of Fluconazole API. Toward the end of Q3, the values accessed at USD 150850/MT with an average quarterly inclination of 1.78%.
Europe
In the third quarter of 2022, Fluconazole API market sentiments in Europe remained tormented. The Fluconazole API trade market decelerated in the European region throughout the quarter due to stable prices of feed methanol globally, sufficient supply, and bearish demand from end-user industries. To cope with the rising inflation, the government rose the interest rates to bring down the consumer's request, eventually forcing the domestic merchants to quote lower values. Also, enough inventories and a stable supply chain kept the market sentiments feeble. Toward the end of Q3, the values accessed at USD 158890/MT with an average quarterly declination of 3.33%.
For the Quarter Ending June 2022
North America
In the second quarter of 2022, Fluconazole API market sentiments in North America remained mixed. The Fluconazole API trade market decelerated in North America during the first half of Q2 2022 due to stable prices of feed methanol globally, sufficient supply, and bearish demand from end-user industries. Prices rose marginally at the onset second half of Q2 owing to the tightness of natural gas in the USA's market and high energy demand. The increase in supplies and weak trading activities contributed to the downward trend. Also, with low manufacturing costs and sluggish demand, cost-cutting was experienced by the Fluconazole market. Toward the end of Q2, the values accessed at USD 158950/MT with a quarterly declination of 1.17%.
Asia
During the second quarter of 2022, the Fluconazole API market witnessed an upward trajectory due to increasing feed prices and fluctuating demand from downstream pharmaceutical industries. With the commencement of Q2 2022, the prices of feed methanol were hiked, affecting the prices of Fluconazole to increase in the domestic market. Towards the termination of the first half of Q2 2022, feed methanol prices slumped, prompting the decrease of Fluconazole prices in the Asian Pacific region. Also, the demand from downstream end-user industries went stable. Toward the end of Q2, the values accessed at USD 143140/MT with a quarterly inclination of 3.43%%.
Europe
In the second quarter of 2022, Fluconazole showcased an oscillating price movement in the European market because of the increased prices of feed Methanol from the regional market. At the outset of Q2 2022, feed Methanol prices showcased a stable trajectory globally, propelling the prices of Fluconazole to decrease in the regional market. Substantial cost inflation in drug prices boosted the API market in the second half of Q2 2022. At the termination of Frist half of Q2 2022, Fluconazole prices witnessed a stable increase owing to increased feedstock methanol cost and surging inquiries from the pharmaceutical sector. By Q2 2022, prices were recorded to drop with values accessed at USD 176000/MT with a quarterly declination of 0.53%.
