For the Quarter Ending September 2025
North America
• In the United States, Itraconazole Price Index rose in Q3 2025, driven by strengthening pharmaceutical demand and rising input costs.
• Itraconazole production costs increased during Q3 2025, influenced by a 2.6% year-over-year PPI rise in August 2025.
• Demand for Itraconazole strengthened in Q3 2025, supported by increased FDA drug approvals in the pharmaceutical sector.
• The Itraconazole Price Index faced upward pressure from firming feedstock costs and robust sector demand in Q3 2025.
• Rising CPI (3.0% year-over-year in September 2025) signaled higher operational costs; consumer confidence also declined.
• Strong retail sales (5.42% year-over-year in September 2025) and low unemployment (4.3% in September 2025) supported healthcare spending.
• Natural gas prices, a key methanol feedstock, reached a two-year high in Q3 2025, impacting production costs.
• Industrial production saw a marginal 0.1% year-over-year increase in September 2025, indicating broader economic stagnation.
Why did the price of Itraconazole change in September 2025 in North America?
• Rising input costs, with PPI increasing 2.6% year-over-year in August 2025, pressured Itraconazole prices upward.
• Strengthening US pharmaceutical sector demand in Q3 2025, driven by new drug approvals, supported Itraconazole price increases.
• Higher natural gas prices in Q3 2025, impacting methanol feedstock, increased Itraconazole production expenses.
Europe
• In Germany, the Itraconazole Price Index fell in Q3 2025, due to easing basic chemical producer prices and intensified imports.
• Itraconazole production costs faced upward pressure from elevated overall raw material and high energy costs in Q3 2025.
• Demand for pharmaceutical products in Germany strengthened in Q3 2025, supporting the Itraconazole demand outlook.
• The Manufacturing Index showed a contracting trend in September 2025, reflecting a broader slowdown in German industrial activity.
• Industrial Production in Germany declined by 1.0% year-over-year in September 2025, impacting overall supply chain stability.
• Consumer Price Index rose 2.4% year-over-year in September 2025, while Producer Price Index declined 1.7%.
• Unemployment remained low at 3.9% in September 2025, supporting consumer spending and healthcare demand.
• High carbon allowance costs continued to pressure European chemical companies, influencing Itraconazole price forecasts in Q3 2025.
Why did the price of Itraconazole change in September 2025 in Europe?
• Producer Price Index declined 1.7% in September 2025, easing basic chemical input costs.
• Imports of pharmaceutical products into Germany intensified in Q3 2025, increasing overall supply.
• Elevated raw material and high energy costs continued to pressure Itraconazole production expenses in Q3 2025.
APAC
• In China, the Itraconazole Price Index declined quarter-over-quarter in Q3 2025, driven by persistent industry overcapacity.
• The Itraconazole Price Forecast suggests continued downward pressure, influenced by cautious consumer confidence in September 2025.
• Itraconazole Production Cost Trend saw input cost inflation ease in September 2025, following August's raw material price increases.
• Itraconazole Demand Outlook remained subdued in Q3 2025, despite strengthening demand for specialty chemicals.
• The Itraconazole Price Index faced bearish pressure from a contracting Manufacturing Index in September 2025.
• China's CPI declined by 0.3% year-on-year in September 2025, indicating broader deflationary pressures.
• PPI fell by 2.3% year-on-year in September 2025, reducing factory-gate prices for Itraconazole manufacturers.
• Industrial production expanded by 6.5% year-on-year in September 2025, supporting stable supply chains.
• Stable retail sales, up 3.0% year-on-year in September 2025, indirectly supported healthcare funding.
• A stable unemployment rate of 5.2% in September 2025 supported consumer income and healthcare access.
Why did the price of Itraconazole change in September 2025 in APAC?
• China's CPI declined by 0.3% in September 2025, signaling overall deflationary pressures.
• The Manufacturing Index contracted in September 2025, reflecting economic weakness and subdued demand.
• Persistent overcapacity in China's chemical industry throughout Q3 2025 amplified supply.
For the Quarter Ending December 2022
North America
The Itraconazole market in the North American region fluctuated in the fourth quarter of 2022. Prices started to rise in Q4 2022 and kept growing due to high manufacturing costs, numerous logistical problems, and rising inflation through the second month of the fourth quarter.
Growing transportation costs and congestion at the key ports also helped maintain the market position. Furthermore, confusion and a slowdown in API output due to rising energy prices had a favorable effect on the market. Prices begin to decrease later in December as a result of falling inflation and decreasing end-user sector demand as the holiday season approaches. Towards the termination of Q4 2022, the prices of itraconazole API accessed at USD 366560/MT with an average quarterly inclination of 0.12%.
Asia
The Asia Pacific region experienced generally unchanged market sentiments for the itraconazole API during the fourth quarter of 2022. Due to strong demand from downstream pharmaceutical businesses, prices started to rise steadily at the beginning of the fourth quarter. Zero-covid policies and the installation of lockdowns both had an impact on the market environment. Later, as Q4 2022's second month got underway, lower production costs, sufficient stockpiles, and a strong supply caused the itraconazole API price trajectory to exhibit a stable trend. The domestic market was also sustained by steady end-user demand. Towards the termination of Q4 2022, the itraconazole API market prices were recoded as USD 345200/MT FOB Shanghai with an average quarterly inclination of 0.53%.
Europe
Itraconazole pricing in the European region exhibited a see-saw trend in the fourth quarter of 2022. The demand for itraconazole API in the pharmaceutical industry's downstream market was seen to be steady. In the first two months of Q4 2022, price increases were caused by the continuous port congestion and supply disruption in the European region. The trend of itraconazole was also impacted by increased freight costs. However, due to a decline in inflation, relief from port congestion, and a small amount of inventory held by domestic retailers, prices fell significantly in the month of December. Towards the termination of Q3 2022, the Itraconazole API market prices were recoded as USD 371820/MT CFR Hamburg with an average quarterly inclination of 0.12%.
For the Quarter Ending September 2022
North America
In the North American region, Itraconazole API witnessed firm market sentiments in the third Quarter of 2022. Itraconazole API prices showcased a rising trend throughout the Quarter, owing to steady demand from downstream pharmaceutical industries. Furthermore, the price of raw material toluene also showcased an increasing trend globally with increasing energy values. With low operating rates and a supply crunch, the market experienced stable sentiments. Furthermore, the increased freight charge also affected the Itraconazole API market. Towards the termination of Q3 2022, the prices of Itraconazole API showed a rising trajectory with values accessed at USD 410580 /MT with an average quarterly inclination of 0.94%.
Asia
In the third Quarter of 2022, the Itraconazole API witnessed rising market sentiments in the Asia Pacific region. Throughout this Quarter, the prices increased gradually owing to firm demand from downstream pharmaceutical industries. Also, the hovering prices of Raw material toluene on the higher end affected the Itraconazole API market sentiments. Less production cost, enough inventories, and good supply prompted the Itraconazole API price trajectory to witness a stable trend. Stable demand from the end-user industry also stabilized the domestic market. Towards the termination of Q3 2022, the Itraconazole API market prices were recoded as USD 346850/MT FOB Shanghai with an average quarterly inclination of 1.16%.
Europe
In the third Quarter of 2022, the Itraconazole API in the European market was observed with stable market sentiments throughout the Quarter, taking cues from the ease in demand. Due to sinking demand from downstream pharmaceutical industries, the price was accessed to be firm. Also, enough inventories and low manufacturing costs kept the values at ease. The ease in the ongoing energy crisis in Europe prevailed its impact on the manufacturing facilities' operational loads. Towards the termination of Q3 2022, the Itraconazole API market prices were recoded as USD 375320/MT FOB Shanghai with an average quarterly inclination of 0.01%.
