For the Quarter Ending September 2025
North America
• In United States, the Loperamide Hydrochloride Price Index rose quarter-over-quarter in Q3 2025, driven by escalating production costs.
• Production costs increased due to a 2.6% PPI rise in August 2025 and tariffs on imported Active Pharmaceutical Ingredients.
• Loperamide Hydrochloride demand was supported by a 5.42% increase in retail sales in September 2025.
• Consumer spending on OTC medications remained robust, despite declining consumer confidence to 94.2 in September 2025.
• Raw material inventories for US chemical manufacturers contracted in Q3 2025, impacting supply dynamics.
• US pharmaceutical exports decreased in July 2025, while imports increased.
• The Biotech and Pharma Market Performance showed a firm trajectory in Q3 2025, supporting sector stability.
Why did the price of Loperamide Hydrochloride change in September 2025 in North America?
• Production costs rose from a 2.6% PPI increase in August 2025 and new API tariffs.
• Strong consumer demand for OTC drugs was supported by a 5.42% retail sales increase in September 2025.
• Contracting raw material inventories and increased industrial electricity prices in September 2025 impacted supply.
APAC
• In China, the Loperamide Hydrochloride Price Index fell quarter-over-quarter in Q3 2025, driven by deflationary pressures and weak domestic demand.
• Loperamide Hydrochloride production costs declined in Q3 2025, as PPI fell -2.3% year-on-year in September 2025.
• Demand faced headwinds from a 5.2% unemployment rate and 89.6 consumer confidence in September 2025.
• Despite economic moderation, China's pharmaceutical market experienced robust growth in Q3 2025, driven by an aging population.
• Manufacturing Index was Contracting in September 2025, yet industrial production expanded 6.5% year-on-year.
• Elevated global petrochemical oversupply and China's crude inventories built up in Q3 2025.
• China's total exports and imports rose in Q3 2025, with pharmaceutical and API exports growing strongly.
• Global overcapacity in chemical building blocks persisted in Q3 2025, prompting efforts to address sector oversupply.
Why did the price of Loperamide Hydrochloride change in September 2025 in APAC?
• Deflationary pressures from a -0.3% CPI year-on-year in September 2025 dampened consumer demand.
• Weak industrial demand, reflected by -2.3% PPI year-on-year in September 2025, lowered production costs.
• Contracting Manufacturing Index in September 2025 and persistent global overcapacity influenced supply-demand balance.
Europe
• In Germany, the Loperamide Hydrochloride Price Index remained upward quarter-over-quarter in Q3 2025, amidst conflicting cost and demand pressures.
• Loperamide Hydrochloride production costs faced upward pressure from elevated energy and raw material expenses in Q3 2025.
• Demand for Loperamide Hydrochloride was supported by a moderately growing pharmaceutical market in Q3 2025.
• Germany's Manufacturing Index contracted in Q3 2025, and industrial production declined 1.0% in September 2025.
• Capacity utilization dropped in September 2025, while German chemical exports declined in Q3 2025 due to US tariffs.
• The Consumer Price Index rose 2.4% in September 2025, contributing to general inflationary pressures on raw materials.
• Producer prices of industrial products declined 1.7% in September 2025, primarily due to lower energy prices.
Why did the price of Loperamide Hydrochloride change in September 2025 in Europe?
• Production costs faced upward pressure from a 2.4% CPI rise in September 2025.
• Lower producer prices, down 1.7% in September 2025, eased some production cost burdens.
• Demand was supported by stable retail sales, up 0.2% in September 2025, and pharmaceutical growth.
