For the Quarter Ending September 2025
North America
• In United States, the Naltrexone Hydrochloride Price Index rose in Q3 2025, driven by increasing production costs and tightening supply.
• Naltrexone Hydrochloride production costs increased in Q3 2025, influenced by a 2.6% PPI rise in August 2025.
• Energy costs for Naltrexone Hydrochloride rose, with US natural gas and industrial electricity prices increasing in September 2025.
• Naltrexone Hydrochloride demand outlook strengthened in Q3 2025, supported by robust US pharmaceutical market sentiment.
• Consumer spending, up 5.42% in September 2025, and a 4.3% unemployment rate supported Naltrexone Hydrochloride demand.
• US chemical production levels turned negative in Q3 2025, despite a 0.1% industrial production growth in September 2025.
• Manufacturing inventories tightened in Q3 2025 due to accelerated destocking, impacting Naltrexone Hydrochloride supply.
• Inflationary pressures, with a 3.0% year-over-year CPI increase in September 2025, elevated overall manufacturing expenses.
• Consumer confidence declined to 94.2 in September 2025, influenced healthcare spending decisions.
Why did the price of Naltrexone Hydrochloride change in September 2025 in North America?
• Rising raw material and operational expenses increased Naltrexone Hydrochloride production costs.
• Tightening US manufacturing inventories and contracting chemical production constrained supply.
• Upward natural gas and industrial electricity prices elevated Naltrexone Hydrochloride manufacturing expenses.
APAC
• In China, the Naltrexone Hydrochloride Price Index fell in Q3 2025, influenced by persistent overcapacity and intensified competition.
• Naltrexone Hydrochloride production costs declined in September 2025, as the Producer Price Index (PPI) fell by 2.3% year-on-year.
• Demand for Naltrexone Hydrochloride faced headwinds in September 2025 due to a contracting Manufacturing Index.
• Industrial production rose 6.5% year-on-year in September 2025, supporting the Naltrexone Hydrochloride demand outlook.
• Raw material inventories for manufacturing decreased in July and August 2025, with the decline narrowing in September.
• China's chemical exports surged in Q3 2025, driven by competitive pricing and domestic overcapacity.
• Consumer confidence remained cautious (89.6 index) in September 2025, impacting discretionary healthcare spending.
• High-tech manufacturing output outperformed in Q3 2025, indicating robust sector-specific demand drivers.
Why did the price of Naltrexone Hydrochloride change in September 2025 in APAC?
• China's Producer Price Index (PPI) fell 2.3% year-on-year in September 2025, reducing Naltrexone Hydrochloride production costs.
• Persistent overcapacity in China's chemical markets intensified competition for Naltrexone Hydrochloride during Q3 2025.
• A contracting Manufacturing Index in September 2025 signaled weaker overall industrial demand.
Europe
• In Germany, Naltrexone Hydrochloride Price Index rose in Q3 2025, influenced by elevated raw material and energy costs.
• Naltrexone Hydrochloride production costs increased in Q3 2025, driven by elevated raw material and strengthened electricity prices.
• The Producer Price Index declined by 1.7% year-over-year in September 2025, offering relief to Naltrexone Hydrochloride input costs.
• The Consumer Price Index increased by 2.4% year-over-year in September 2025, raising Naltrexone Hydrochloride operational expenses.
• Expanded pharmaceutical output in July 2025 supported Naltrexone Hydrochloride demand, despite deteriorating business sentiment.
• A low unemployment rate of 3.9% in September 2025 bolstered Naltrexone Hydrochloride demand by supporting healthcare funding.
• The Manufacturing Index trended contracting in September 2025, signaling a slowdown in German manufacturing.
• Industrial production declined by 1.0% year-over-year in September 2025, affecting Naltrexone Hydrochloride supply stability.
Why did the price of Naltrexone Hydrochloride change in September 2025 in Europe?
• Elevated raw material costs and strengthened electricity prices increased Naltrexone Hydrochloride production expenses in Q3 2025.
• The Consumer Price Index increased by 2.4% year-over-year in September 2025, raising Naltrexone Hydrochloride operational costs.
• Industrial production declined by 1.0% year-over-year in September 2025, impacting supply amidst contracting manufacturing.
For the Quarter Ending December 2022
North America
During quarter 4 of 2022 in North America, the CFR Los Angeles price for Naltrexone Hydrochloride increased from $6942000/mt to $6965000/mt in October and November before falling to $6915000/mt in December. Due to China's Golden Week holiday, Naltrexone Hydrochloride imports were suspended during the first week of October.
Considering the huge inventories of the product, domestic suppliers were able to match the demand for most of the quarter. Hitherto, offtakes in the end-user industries remained above average. The market for Naltrexone Hydrochloride saw a pattern change in the second part of the quarter as a result of the unexpected rise in Covid cases in China. Nevertheless, as the economy grew and there was a significant decline in port backlog in December, the disrupted supply chain did progressively mend.
Asia Pacific
During the fourth quarter of 2022, the price of Naltrexone Hydrochloride across the Asia Pacific region showed a stagnant market trend. Ex-Mumbai values in India first increased from $5556377.67/mt to $56876521.1/mt in October and November before dropping to $5605025.23/mt in December. The first week of October saw a steady decline in Naltrexone Hydrochloride orders for China's API market as a result of the shutdown of manufacturing facilities for the Golden Week. It was challenging for the market to catch up to the slight growth seen in some downstream businesses because Chinese traders had to deal with a variety of conflicting signals after a one-week break, but strong demand kept the market afloat. Chinese suppliers and producers were able to meet the entire quarter's demand thanks to ample supplies there. The administration amended its zero-covid rules in response to criticism and significant unrest in the nation, leaving the nation vulnerable once more.
Europe
Prices for Naltrexone Hydrochloride decreased slightly in Europe during the fourth quarter of 2022, with CFR Hamburg values falling from $7027570/mt to $7020000/mt between October and December. International demand was stronger in the initial half of the quarter than it was in December because of the unanticipated increase in COVID cases, which caused a steady decline in demand. Demand in Germany remained high despite rising costs for energy and raw materials in the end-user sectors.
For The Quarter Ending September 2022
North America
During the quarter ending in September 2022, the cost of Naltrexone Hydrochloride in the North American market showed a consistent downward trend. With a progressive decline in downstream pharmaceutical sector demand, the price value of Naltrexone Hydrochloride fell on the domestic market. Additionally, the market price of the raw material hydrochloric acid was marginally dropping throughout the third quarter of 2022, which kept the cost of Naltrexone Hydrochloride in check. Overall, the third quarter of 2022 saw relatively steady prices for Naltrexone Hydrochloride due to constancy in downstream demand, upstream manufacturing costs, and supply. The prices for Naltrexone Hydrochloride were recorded and settled at USD 6922500/MT CFR Los Angeles, with an average quarterly declination of 0.57%.
APAC
The price of Naltrexone Hydrochloride in the Asia-Pacific area exhibited a constant trajectory for the quarter ending in September 2022. As demand from pharmaceutical companies climbed modestly, so did the price of Naltrexone Hydrochloride. Additionally, because the market price of the feedstock hydrochloric acid rose only modestly throughout the entire quarter, the price of naltrexone hydrochloride was kept in check. Due to consistency in downstream demand, upstream manufacturing costs, and supply, Naltrexone Hydrochloride prices in the third quarter of 2022 were largely stable. The prices for Naltrexone Hydrochloride were recorded and settled at INR 457500000/MT Ex-Mumbai with the average quarterly inclination of 0.59%.
Europe
In line with the North American market, the cost of naltrexone hydrochloride dropped in the European region during the third quarter of 2022. Pharmaceutical businesses, domestic suppliers, and merchants were forced to keep the price of Naltrexone Hydrochloride lower to retain the margin due to existing stockpiles and adequate supply. Additionally, while the market for the feedstock hydrochloric acid declined gradually throughout the third quarter, the price of Naltrexone Hydrochloride was kept under control. The average quarterly decline in Naltrexone Hydrochloride prices was 1.71%, and the prices were recorded and finalized at USD 7007880/MT CFR Hamburg.
For the Quarter Ending June 2022
North America
The price of Naltrexone Hydrochloride showcased a stable increment in the North American market during the quarter ending in June 2022. As the downstream demand for Naltrexone Hydrochloride from pharma industries to cure opioid overdose was marginally increasing in the domestic market, so did its price value. Besides, the market value of feedstock Hydrochloric Acid was surging peripherally during the first half of second quarter, which kept the manufacturing cost of Naltrexone Hydrochloride stable and its prices in check. Altogether, owing to the consistency in downstream demand, upstream manufacturing cost, and supply, the Naltrexone Hydrochloride prices remained nearly stable throughout the second quarter of the year 2022. The prices for Naltrexone Hydrochloride were recorded and settled at USD 7193333/MT CFR Los Angeles.
APAC
In the Asia-Pacific region, the cost of Naltrexone Hydrochloride showed a steady rise for the quarter ending in June 2022, mimicking the North American market. The price of Naltrexone Hydrochloride increased slightly along with the amount that pharmaceutical firms needed for treating opiate overdoses in the domestic market. In addition, the cost of Naltrexone Hydrochloride was maintained in check because the market value of the feedstock Hydrochloric Acid increased little throughout the entire quarter. Overall, the second quarter of 2022 had somewhat consistent pricing for Naltrexone Hydrochloride due to constancy in downstream demand, upstream manufacturing costs, and supply. The prices for Naltrexone Hydrochloride were recorded and settled at INR 449500000/MT Ex-Mumbai.
Europe
Mirroring the North American market, the price of Naltrexone Hydrochloride increased marginally in the European countries during the quarter ending in June 2022. Because pharmaceutical companies needed more Naltrexone Hydrochloride to treat opiate overdoses in the domestic market, the price of the drug climbed slightly at the same time. Additionally, the cost of Naltrexone Hydrochloride was controlled as minimal growth was seen in the feedstock hydrochloric acid's market price over the entire quarter. Due to consistency in downstream demand balanced with the supply side, Naltrexone Hydrochloride prices in the second quarter of 2022 were reasonably stable. The prices for Naltrexone Hydrochloride were recorded and settled at USD 7100000 /MT CFR Hamburg.
