Phenylephrine Hydrochloride Prices, Trends, Index, News, Monitor and Demand

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Phenylephrine Hydrochloride

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Phenylephrine Hydrochloride Price Trend and Forecast

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Market Overview

For the Quarter Ending September 2025

North America

• In the United States, the Phenylephrine Hydrochloride Price Index remained stable in Q3 2025, as increasing imports tempered cost pressures.

• Production costs for Phenylephrine Hydrochloride rose, driven by a 2.6% year-over-year PPI increase in August 2025.

• Demand for Phenylephrine Hydrochloride saw a resurgence within the pharmaceutical sector during Q3 2025.

• Overall chemical industry inventories shrank in Q3 2025 due to accelerating destocking activities.

• Energy and feedstock costs, including natural gas, increased in Q3 2025; CPI rose 3.0% in September 2025.

• US retail sales, excluding auto and gas, increased 5.42% year-over-year in September 2025, supporting consumer demand.

• US chemical production contracted in Q3 2025, despite a marginal 0.1% year-over-year industrial production increase.

• Consumer confidence declined in September 2025, reflecting reduced optimism, while unemployment remained stable at 4.3%.

Why did the price of Phenylephrine Hydrochloride change in September 2025 in North America?

• Rising input and raw material costs, evidenced by a 2.6% PPI increase in August 2025, pressured prices upward.

• Increasing phenol imports from Asia tempered potential price gains in the US during Q3 2025.

• Strong retail sales, up 5.42% year-over-year in September 2025, supported demand, counteracting price pressures.

APAC

• In China, the Phenylephrine Hydrochloride Price Index fell quarter-over-quarter in Q3 2025, driven by declining producer prices.

• Phenylephrine Hydrochloride production costs decreased as PPI fell 2.3% in September 2025, reflecting lower input costs.

• Consumer confidence remained low at 89.6 in September 2025, dampening demand for health products.

• The Manufacturing Index was contracting in September 2025, reflecting a slowdown in industrial activity.

• Retail sales grew 3.0% in September 2025, supporting demand for OTC Phenylephrine Hydrochloride medications.

• Overall chemical inventories remained elevated in China during Q3 2025, reflecting persistent oversupply conditions.

• Benzene prices, a key precursor, stabilized in early Q3 2025, with spot prices dipping slightly.

• China's industrial production increased 6.5% in September 2025, supporting the broader manufacturing sector.

• CPI fell 0.3% in September 2025, reflecting weak consumer demand and lower overall prices.

Why did the price of Phenylephrine Hydrochloride change in September 2025 in APAC?

• Producer prices declined 2.3% in September 2025, reducing manufacturing input costs for Phenylephrine Hydrochloride.

• Elevated chemical inventories and expanding phenol capacity contributed to an oversupply sentiment in Q3 2025.

• Weak consumer confidence at 89.6 and a contracting Manufacturing Index impacted overall demand.

Europe

• In Germany, the Phenylephrine Hydrochloride Price Index fell quarter-over-quarter in Q3 2025, influenced by declining feedstock costs.

• Phenylephrine Hydrochloride production costs faced downward pressure in Q3 2025 due to declining phenol and benzene prices.

• High energy and personnel costs in Germany strained Phenylephrine Hydrochloride production margins throughout Q3 2025.

• Pharmaceutical market demand for Phenylephrine Hydrochloride in Germany moderately expanded during Q3 2025.

• Overall German chemical industry demand for Phenylephrine Hydrochloride weakened significantly in Q3 2025.

• Phenol inventory levels swelled in Germany during Q3 2025, contributing to an oversupply of this key precursor.

• Germany's Manufacturing Index was contracting in Q3 2025, reflecting a broader industrial slowdown.

• The Consumer Price Index rose 2.4% in September 2025, alongside a 6.3% unemployment rate, impacting OTC demand.

• Producer prices declined 1.7% in September 2025, while retail sales rose 0.2% and industrial production fell 1.0%.

Why did the price of Phenylephrine Hydrochloride change in September 2025 in Europe?

• Feedstock phenol and benzene costs declined in Q3 2025, reducing Phenylephrine Hydrochloride production expenses.

• Germany experienced a surge in cheap chemical imports from China in Q3 2025, increasing market supply.

• Overall German chemical industry demand weakened significantly in Q3 2025, despite pharmaceutical sector expansion

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List of Phenylephrine Hydrochloride Suppliers

1. Midas Pharma GmbH
2. Shreeji Pharma International
3. Zhejiang Hisoar Chuannan Pharmaceutical Co. Ltd.
4. Divi's Laboratories Ltd.
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Product Description

Phenylephrine Hydrochloride is a small‑molecule pharmaceutical active substance belonging to the class of sympathomimetic amine compounds — specifically, an α₁‑adrenergic receptor agonist. Chemically, it is the hydrochloride salt of Phenylephrine (the (R)-enantiomer), typically isolated and purified to pharmacopeial standards (e.g., USP/EP). Its molecular formula is C₉H₁₃NO₂·HCl and the molecular weight is approximately 203.67 g/mol. As a manufactured chemical compound, Phenylephrine Hydrochloride is obtained through controlled synthetic processes under Good Manufacturing Practice (cGMP) conditions, yielding a high‑purity crystalline powder—usually white or almost white, odorless (or nearly so), with a bitter taste. In its pure form it is freely soluble in water and in alcohol, with a melting point typically in the range of 140–145 °C. Phenylephrine Hydrochloride’s key chemical property is its ability to act as a selective α₁‑adrenergic receptor agonist. This confers vasoconstrictive action — i.e., it causes contraction of vascular smooth muscle — which underlies its principal functional attributes. Through this mechanism it narrows blood vessels, thereby reducing swelling in mucosal tissues, increasing peripheral vascular resistance, and raising blood pressure. Because of its broad use in over‑the‑counter (OTC) medications and prescription drugs across multiple delivery forms (tablets, nasal sprays/drops, syrups, ophthalmic drops, injections), Phenylephrine Hydrochloride remains a key API in both cold/allergy therapeutics and cardiovascular / supportive care applications.

Track Phenylephrine Hydrochloride price trend and forecast in top 10 leading countries worldwide.

Phenylephrine Hydrochloride Price Trend and Forecast

Ganesha LG ― Analyst – Cost – Product Engineering Wesco ―

Elizabeth Taluga ― Category Manager Leading Paint Manufacturer ―

Gabino Isla ― Director Feno Resinas ―

Ganesha LG
― Analyst – Cost – Product Engineering Wesco ―

Elizabeth Taluga
― Category Manager Leading Paint Manufacturer ―

Gabino Isla
― Director Feno Resinas ―