For the Quarter Ending March 2026
Pregabalin Prices in North America
- In United States, the Pregabalin Price Index rose quarter-over-quarter in Q1 2026, reflecting elevated manufacturing costs.
- The Pregabalin Production Cost Trend increased in March 2026 as the Producer Price Index rose 4.0%.
- The Pregabalin Price Index faced upward pressure in March 2026 because consumer inflation reached 3.3%.
- The Pregabalin Demand Outlook strengthened in March 2026, supported by a 4.0% increase in retail sales.
- Stable patient access continued in March 2026, backed by 4.3% unemployment and 91.8 consumer confidence.
- The Manufacturing Index expanded in March 2026, while industrial production grew a modest 0.7% year-over-year.
- Pharmaceutical manufacturing expanded in Q1 2026, driving robust procurement for active pharmaceutical ingredients like pregabalin.
- Natural gas prices, a key energy input, decreased significantly in February 2026 due to milder temperatures.
- Generic pregabalin maintained a stable national supply inventory in Q1 2026, avoiding the active shortage list.
- The Pregabalin Price Forecast indicated upward momentum in March 2026 due to persistent inflation pressures.
Why did the price of Pregabalin change in March 2026 in North America?
- Elevated manufacturing input costs drove prices upward in March 2026, reflecting broader inflationary economic pressures.
- Robust pharmaceutical manufacturing activity in Q1 2026 increased procurement demand for essential active pharmaceutical ingredients.
- Modest industrial production growth of 0.7% in March 2026 constrained the domestic chemical supply availability.
Pregabalin Prices in APAC
- In China, the Pregabalin Price Index rose quarter-over-quarter in Q1 2026, driven by surging oil-linked costs.
- The Pregabalin Production Cost Trend increased in March 2026 as the PPI rose 0.5% year-over-year.
- The Pregabalin Demand Outlook remained steady in March 2026, supported by a 1.0% year-over-year CPI increase.
- Industrial production grew 5.7% year-over-year in March 2026, ensuring ample bulk API supply for the market.
- The Manufacturing Index expanded in March 2026, aligning with surged pharmaceutical API production during Q1 2026.
- Retail sales grew 1.7% and unemployment reached 5.4% in March 2026, pressuring premium branded medication sales.
- The Pregabalin Price Forecast stabilized in Q1 2026 as consumer confidence hit 86.0, limiting healthcare engagement.
- Technical grade diethyl malonate feedstock inventories swelled in Q1 2026, while Chinese export volumes remained robust.
Why did the price of Pregabalin change in March 2026 in APAC?
- Diethyl malonate feedstock costs spiked in Q1 2026 due to surging regional oil-linked energy expenses.
- The PPI rose 0.5% in March 2026, reflecting higher factory-gate prices for essential chemical precursors.
- Pharmaceutical API demand for diethyl malonate feedstock surged in Q1 2026, driving overall market consumption.
Pregabalin Prices in Europe
- In Germany, the Pregabalin Price Index rose quarter-over-quarter in Q1 2026, driven by severe feedstock shortages.
- The Pregabalin Production Cost Trend increased as March 2026 CPI reached 2.7%, reflecting higher energy expenses.
- Despite a -0.2% PPI decline in March 2026, Pregabalin API manufacturer margins faced upstream supply constraints.
- The Manufacturing Index expanded in March 2026, reflecting robust pharmaceutical processing activity for Pregabalin formulations.
- Industrial production remained stagnant at 0.0% in February 2026, while retail sales grew 0.7%, supporting demand.
- A stable 4.2% unemployment rate in February 2026 ensured patient access, boosting the Pregabalin Demand Outlook.
- A major German producer declared force majeure on isovaleraldehyde in Q1 2026, severely restricting local supply.
- Acrylonitrile feedstock costs surged in Q1 2026 as Middle Eastern disruptions extended European transit times.
- The Pregabalin Price Forecast indicated upward pressure in March 2026 due to tightened global inventory levels.
Why did the price of Pregabalin change in March 2026 in Europe?
- Acrylonitrile feedstock costs surged sharply in Q1 2026 due to severe global geopolitical shipping disruptions.
- A major German producer declared force majeure on the critical precursor isovaleraldehyde during Q1 2026.
- Downstream pharmaceutical manufacturing demand strengthened significantly in February 2026, driving up overall regional market consumption.
For the Quarter Ending December 2025
Pregabalin Prices in North America
- In the United States, the Pregabalin Price Index rose quarter-over-quarter in Q4 2025, driven by robust pharmaceutical demand.
- Pregabalin production costs increased in December 2025, as the Producer Price Index rose 3.3% year-over-year.
- Demand for Pregabalin was supported by the US pharmaceutical market's outperformance during Q4 2025.
- The Pregabalin demand outlook remained positive, bolstered by 3.9% retail sales growth year-over-year in December 2025.
- Industrial production expanded 2.0% year-over-year in December 2025, indicating stronger manufacturing activity.
- The US chemical industry experienced significant overcapacity throughout 2025, impacting overall supply dynamics.
- Consumer confidence, at 89.1 in December 2025, supported spending despite a 2.7% CPI rise.
- A low unemployment rate of 4.4% in December 2025 indicated a strong labor market and consumer purchasing power.
Why did the price of Pregabalin change in December 2025 in North America?
- Rising input costs, evidenced by a 3.3% year-over-year increase in the Producer Price Index in December 2025.
- Strong demand from the healthcare/pharmaceuticals sector, which outperformed in Q4 2025.
- Robust consumer spending, with retail sales increasing 3.9% year-over-year in December 2025.
Pregabalin Prices in APAC
- In China, Pregabalin Price Index remained stable in Q4 2025, influenced by weak demand and mixed production costs.
- Pregabalin production costs faced upward pressure from elevated urea feedstock costs in November 2025.
- However, the Producer Price Index declined by 1.9% year-over-year in December 2025, easing overall producer-level prices.
- Pregabalin demand was subdued in Q4 2025, with retail sales growth at 0.9% year-over-year in December 2025.
- Consumer confidence cooled in Q4 2025, impacting prescription drug demand due to cautious spending.
- China's industrial production grew 5.2% year-over-year in December 2025, supporting stable pharmaceutical supply chains.
- The Manufacturing Index expanded in December 2025, indicating growth in the broader industrial environment.
- Medicine exports from China, including APIs, steadily increased in the first 11 months of 2025.
- The prices for Pregabalin in Q4, 2025 settled at USD 60,000/MT in Asia.
Why did the price of Pregabalin change in December 2025 in APAC?
- Weak consumer spending, with 0.9% retail sales growth in December 2025, dampened Pregabalin demand.
- Producer Price Index declined 1.9% year-over-year in December 2025, easing overall production costs.
- Elevated urea feedstock costs in November 2025 and rising sulfur costs in Q4 2025 pressured costs.
Pregabalin Prices in Europe
- In Germany, the Pregabalin Price Index fell quarter-over-quarter in Q4 2025, influenced by decreasing producer costs and competitive pressures.
- Pregabalin production costs declined as the Producer Price Index decreased by 2.5% year-over-year in December 2025.
- Despite a 1.8% rise in the Consumer Price Index in December 2025, overall producer input costs for Pregabalin decreased.
- High energy and raw material costs, particularly natural gas, persistently burdened the German chemical industry throughout 2025.
- Demand for Pregabalin was supported by moderate pharmaceutical market growth in 2025, driven by an aging population.
- Retail sales increased by 1.8% year-over-year in December 2025, indirectly supporting healthcare spending and patient access.
- The unemployment rate remained low at 3.8% in December 2025, contributing to stable patient affordability for medications.
- Industrial production remained stable at 0.0% year-over-year in October 2025, reflecting a stagnant broader economic environment.
Why did the price of Pregabalin change in December 2025 in Europe?
- The Producer Price Index decreased by 2.5% year-over-year in December 2025, reducing manufacturing input costs.
- Increased competitive pressures from abroad prompted German chemical companies to lower price plans in October 2025.
- Weak external demand and low consumer confidence (-12.0 in December 2025) dampened overall market sentiment.
For the Quarter Ending September 2025
APAC
- In China, the Pregabalin Price Index fell quarter-over-quarter in Q3 2025, driven by weak consumer demand.
- Pregabalin production costs were stable in Q3 2025, influenced by steady petrochemical feedstock costs.
- The demand outlook for Pregabalin faced moderation due to overall economic growth slowing in China during Q3 2025.
- China's Consumer Price Index declined 0.3% year-over-year in September 2025, signaling deflation and reduced purchasing power.
- Producer Price Index decreased 2.3% year-over-year in September 2025, reflecting lower input costs and weak industrial demand.
- The Manufacturing Index contracted in September 2025, indicating reduced industrial activity impacting the supply chain.
- Industrial production grew 6.5% year-over-year in September 2025, supporting a stable supply of chemical precursors.
- Global overcapacity in the chemicals sector, significantly influenced by China's expanding production, persisted in Q3 2025.
Why did the price of Pregabalin change in September 2025 in APAC?
- Weak consumer demand, with CPI declining 0.3% in September 2025, pressured Pregabalin prices.
- Producer Price Index fell 2.3% in September 2025, reflecting lower input costs and weak industrial demand.
- Contracting Manufacturing Index and 5.2% unemployment in September 2025 dampened overall market confidence.
Europe
- In Germany, the Pregabalin Price Index remained stable quarter-over-quarter in Q3 2025, balancing declining petrochemical costs with strong demand.
- Pregabalin production costs were influenced by a 1.7% decline in producer prices in September 2025, driven by lower energy costs.
- Elevated natural gas and electricity prices in Q3 2025 continued to challenge overall chemical manufacturing costs.
- Demand for Pregabalin saw a boost in Q3 2025, as German pharmaceutical sector output firmed.
- The Manufacturing Index contracted in Q3 2025, indicating broader industrial weakness, potentially impacting supply chains.
- Industrial production declined by 1.0% in September 2025, reflecting a weaker manufacturing environment for intermediates.
- Retail sales increased by 0.2% in September 2025, supporting stable consumer spending and healthcare system funding.
- The unemployment rate remained stable at 6.3% in September 2025, contributing to consistent consumer purchasing power.
- Pregabalin price forecast suggests continued stability, with strong pharmaceutical demand offsetting persistent high energy costs.
Why did the price of Pregabalin change in September 2025 in Europe?
- Producer prices fell 1.7% in September 2025, due to lower energy costs, reducing Pregabalin manufacturing expenses.
- Strong pharmaceutical demand in Q3 2025, with firming sector output, provided upward pressure on Pregabalin prices.
- Elevated natural gas and electricity prices in Q3 2025 continued to exert upward pressure on Pregabalin production costs.
North America
- In United States, the Pregabalin Price Index rose quarter-over-quarter in Q3 2025, driven by increasing production costs and robust pharmaceutical demand.
- Pregabalin production costs increased due to a 2.6% rise in PPI in August 2025 and strengthened natural gas prices in September 2025.
- Pregabalin demand outlook was supported by robust US pharmaceutical demand in 2025 and a 5.42% rise in retail sales in September 2025.
- Wholesale chemical inventories eased in July 2025, suggesting a balanced supply-demand environment.
- US chemical imports rose in July 2025, narrowing the chemical trade surplus for the quarter.
- Overall industrial production saw a marginal 0.1% year-over-year increase in September 2025, indicating slower economic expansion.
- Declining consumer confidence and a 4.3% unemployment rate in September 2025 impacted healthcare spending.
- The 3.0% year-over-year CPI increase in September 2025 contributed to higher operational costs for manufacturers.
- US manufacturing output rose in August 2025, following a July decrease, indicating some industrial activity recovery.
Why did the price of Pregabalin change in September 2025 in North America?
- Production costs increased due to a 2.6% rise in PPI in August 2025 and strengthened natural gas prices.
- Robust US pharmaceutical demand in 2025 supported prices, despite declining consumer confidence in September 2025.
- Wholesale chemical inventories eased in July 2025, influencing supply dynamics and price stability.
