For the Quarter Ending September 2025
North America
• In United States, Sulfamethoxazole Price Index fell in Q3 2025, due to oversupply and deteriorating chemical demand.
• Production costs for Sulfamethoxazole rose in Q3 2025, with PPI up 2.6% in August and CPI up 3.0% in September.
• Medical sector demand strengthened during H2 2025, providing support for Sulfamethoxazole consumption.
• Industrial production grew only 0.1% in September 2025, reflecting broader market weakness and falling new orders.
• Chemical industry inventories tightened in Q3 2025, driven by accelerating destocking efforts.
• US chemical import and export volumes contracted in 2025, influenced by tariff friction during Q3 2025.
• Natural gas prices inched up in September 2025, while crude oil prices weakened in July-August 2025.
• Strong retail sales, up 5.42% in September 2025, and low 4.3% unemployment supported human pharmaceutical demand.
• Consumer confidence declined to 94.2 in September 2025, signaling potential headwinds for overall economic activity.
Why did the price of Sulfamethoxazole change in September 2025 in North America?
• Oversupply in the chemical industry during Q3 2025 exerted downward pressure.
• Major customer market demand for chemicals deteriorated in Q3 2025, reducing new orders.
• Rising input/raw materials and energy costs in Q3 2025 increased production expenses.
APAC
• In China, the Sulfamethoxazole Price Index fell quarter-over-quarter, driven by weak industrial demand and falling factory-gate prices.
• Sulfamethoxazole price forecast indicates continued pressure from persistent overcapacity and pessimistic consumer confidence in September 2025.
• Sulfamethoxazole production costs saw mixed trends; benzene feedstock stabilized, but manufacturing input prices jumped in July 2025.
• Demand outlook for Sulfamethoxazole remains sustained by an aging population and chronic diseases in 2025.
• The Sulfamethoxazole Price Index faced downward pressure from -0.3% CPI and -2.3% PPI year-over-year in September 2025.
• China's Manufacturing Index contracted July-August 2025, though new orders and production expanded in September 2025.
• Retail sales grew 3.0% year-over-year in September 2025, supporting consumer spending on healthcare.
• Raw materials inventory for manufacturing remained below threshold in August and September 2025, amidst global overcapacity.
Why did the price of Sulfamethoxazole change in September 2025 in APAC?
• Weak industrial demand, reflected by a contracting Manufacturing Index in September 2025, pressured pricing.
• Falling factory-gate prices, with PPI down -2.3% year-over-year in September 2025, contributed to lower selling prices.
• Persistent global overcapacity in chemical building blocks throughout Q3 2025 created a competitive market.
Europe
• In Germany, the Sulfamethoxazole Price Index fell quarter-over-quarter in Q3 2025, influenced by contracting industrial production.
• Sulfamethoxazole production costs faced pressure from high energy costs and a 2.4% CPI increase in September 2025.
• Benzene feedstock costs were bearish in August 2025; the Producer Price Index decreased by 1.7% in September 2025.
• Sulfamethoxazole demand outlook was mixed; pharmaceutical sector demand strengthened in Q3 2025.
• Overall industrial demand remained weak, with German industrial production declining by 1.0% in September 2025.
• High European benzene stock levels and elevated overall chemical inventories persisted in Q3 2025.
• German chemical export orders trended weak in Q3 2025, impacted by US tariffs on pharmaceutical exports.
• Consumer confidence was negative at -23.6 index in September 2025, despite 0.8% retail sales and 3.9% unemployment.
Why did the price of Sulfamethoxazole change in September 2025 in Europe?
• Contracting manufacturing activity and 1.0% industrial production decline in September 2025 reduced overall demand.
• Bearish benzene feedstock costs in August 2025 and 1.7% PPI decrease in September 2025 eased input costs.
• Weak German export orders and increased US imports intensified competition, pressuring prices in Q3 2025.
For the Quarter Ending December 2022
North America
In the North American region, the fourth quarter of 2022 saw altering market trends for Sulfamethoxazole API. Prices were expected to increase through the second month of the quarter starting with Q4 2022 because of the high cost of manufacturing, numerous logistical issues, and rising inflation.
Rising transportation costs and congestion at the key ports also helped keep the market position strong. Due to easing inflation and lowering end-user sector demand, prices start to drop later in December. During the month of December, the settlement price of Sulfamethoxazole API came down to USD 19340/MT CFR Houston.
Asia
The fourth quarter of 2022 saw a range of sentiments on the Sulfamethoxazole API market. At the commencement of Q4 2022, the prices were recorded to increase till the second month of Q4 on the back of increasing demand from the end-user sector and several logistic issues. Also, the strict zero covid policies and repeated lockdowns in the Chinese provinces affected the market situation. The increased production cost on the back of rising energy prices, and increased domestic manufacturing to cater to regional and international orders, kept the market tight. However, as domestic retailers had sufficient stock on hand later in the month of December, the cost of Sulfamethoxazole API decreased. The market remained poor due to negative consumer sentiment as well. During the month of December, the settlement price of Sulfamethoxazole API came down to USD 16120/MT FOB Shanghai.
Europe
Prices for Sulfamethoxazole API in the European region showed a see-saw tendency in the fourth quarter of 2022. The demand for Sulfamethoxazole API from the pharmaceutical industry was experienced to be steady. The supply chain was impacted by the continuous port congestion and supply disruption in the European region, which resulted in a rise in pricing in the first two months of Q4 2022. The elevated trajectory of Sulfamethoxazole API was also influenced by the high freight costs. Nevertheless, December sees a price decline as a result of rising stocks and declining end-user sector demand. During the month of December, the settlement price of Sulfamethoxazole API came down to USD 21020/MT CFR Hamburg.
For the Quarter Ending September 2022
North America
Due to conflicting market sentiments, Sulfamethoxazole API prices in the North American region showed growing trends at the end of Q3 2022. Due to a reduction in downstream demand, prices remained stable in the first half of Q3 2022. The price of Sulfamethoxazole API remained steady due to the market equilibrium between supply and demand. The cost of API on the domestic market is favorably impacted at the start of the second half by rising downstream direction from the pharmaceutical industry. The domestic merchants kept the quotation at the higher end because of fresh inventories. The price trend was noted with values obtained at USD 19280/MT toward the close of Q3, with an average quarterly inclination of 1.54%.
Asia
The sulfamethoxazole market displayed mixed sentiments throughout the second quarter of 2022. Sulfamethoxazole API prices in the APAC area were impacted during the first and second months of Q3 2022. Production stopped in Chinese provinces because of unfavorable weather and tight zero-covid regulation implications. Prices suddenly decreased because of weak demand from the pharmaceutical industry. The price trend remained lower due to stable demand and supply market sentiments. The destocking of existing supplies also impacted the pricing of Sulfamethoxazole. Beginning with the third month of Q3 2022, supply chain disruption and skewed shipments led to a price hike in Asia-Pacific. The prices reached USD 15860/MT at the end of Q3 with an average quarterly declination of 0.71%
Europe
In the third quarter of 2022, the prices escalated in the European region as the downstream pharmaceutical sector's demand for Sulfamethoxazole increased. At the onset of the first half of Q3 2022, downstream direction from the pharmaceutical industry, owing to favorable market sentiment, kept the prices on the lower side. Later, with the second month's commencement, the prices started to rise owing to increasing demand and insufficient existing inventories among the domestic merchants. Furthermore, the resumption of the pandemic situation, zero covid policy implications, and hindered transportation from the exporting nations also affected the prices of Sulfamethoxazole to be on an increasing trajectory at the end of Q3 2022. Towards the end of Q3 2022, the price trajectory was recorded to be USD 20950/MT with an average quarterly inclination of 0.80%.
For the Quarter Ending June 2022
North America
The prices of Sulfamethoxazole API showcased stable behaviour due to weak market sentiments at the termination of Q2 2022 in the North American region. In the first half of Q2 2022, the prices remained stagnant due to a decline in downstream demand. Equilibrium between the supply and demand side of the market kept the cost of Sulfamethoxazole API on the stable side. At the onset of second half, sluggish downstream demand from the pharmaceutical industry owing to lesser cases of UTIs and bacterial infections also kept the prices on the lower side. Enough inventories, sufficient supplies and steady freight charges also affected the sulfamethoxazole market. Towards the end of Q1, the price trend was recorded to be firm with values accessed at USD 18420/MT with quarterly inclination of 0.2%.
Asia
In the second quarter of 2022, the Sulfamethoxazole market laid out mixed sentiments throughout the quarter. It is one of the products used to treat bacterial diseases, UTIs, etc. At the commencement of first half of Q2 2022, lockdown in Shanghai disrupted the supply chain, distorted shipments prompted price increase in Asia pacific region. At the end of April, due to weak demand from the pharmaceutical sector the prices went down abruptly. Stable demand and supply market sentiments kept the price trajectory on the lower end. Destocking of already available inventories also affected the prices of Sulfamethoxazole. Towards the end of Q2, the value accessed at USD 16210/MT with a quarterly declination of 0.46%.
Europe
In the second quarter of 2022, the prices rise in the European region as the downstream pharmaceutical sector's demand for Sulfamethoxazole increased. At the onset of first half of Q2 2022, Increased downstream demand from the pharmaceutical industry owing to resurfacing pandemic kept the prices on the higher side. With enough existing inventories and sufficient supply, the prices went stable on the lower side at the end of second half of Q2 2022. Ease in the pandemic situation and transport resumption also affected the prices of Sulfamethoxazole to be on decreasing trajectory at the end. Towards the end of Q2 2022, the price trajectory was recorded to be USD 20460/MT with the quarterly inclination of 2.48%.
