Syensqo and Bota Biosciences launch AI-designed, sustainable coffee-derived peptide ingredient delivering multifunctional scalp care benefits and advancing biotech-driven innovation.
Syensqo has introduced an innovative scalp care ingredient, Re2 Coffea Arabica Peptide, marking a significant advancement in sustainable and science-driven personal care solutions. This newly launched active ingredient has been developed in collaboration with Bota Biosciences, reflecting the strong strategic partnership established between the two organizations in 2025. The collaboration underscores a shared commitment to leveraging cutting-edge biotechnology and artificial intelligence to create next-generation solutions for the global personal care market.
Re2 Coffea Arabica Peptide is derived from upcycled coffee grounds that are responsibly sourced from a plantation located in Pu’er, Yunnan, China. By utilizing waste materials from coffee production, the innovation aligns with growing industry and consumer emphasis on sustainability and circular resource use. This approach not only minimizes environmental impact but also enhances the value extracted from natural resources, contributing to more responsible production practices within the beauty and personal care sector.
The ingredient has been specifically designed to support comprehensive scalp health, addressing increasing consumer demand for effective and multifunctional scalp care products. Modern consumers are placing greater importance on scalp wellness, with hydration and soothing emerging as the most sought-after benefits. This trend reflects a broader shift in the hair care industry toward adopting principles traditionally associated with skin care, such as barrier protection, moisture retention, and anti-inflammatory properties.
A key differentiator of Re2 Coffea Arabica Peptide lies in its advanced peptide engineering. Bota Biosciences utilized its integrated physical AI-driven Biofoundry platform to analyze and screen natural proteins found in coffee. Through this process, the most beneficial peptide sequences for scalp health were identified with precision. These peptides were then produced through enzymatic digestion and combined into a single, high-performance active ingredient. The result is a multifunctional solution capable of delivering a range of benefits, including enhanced scalp hydration and softness, improved barrier function, reduced transepidermal water loss (TEWL), minimized redness, and notable anti-inflammatory effects.
According to Vincent Miralles, Global Segment Leader for Hair Care at Syensqo, this innovation represents a significant expansion of the company’s hair actives portfolio. He emphasized that the ingredient’s sustainable sourcing and AI-driven development allow brands to address multiple consumer needs with a single formulation component. This multifunctionality sets a new standard for holistic scalp care performance, offering a unique value proposition in an increasingly competitive market.
The introduction of Re2 Coffea Arabica Peptide also highlights the commercial maturity of Bota Biosciences’ physical AI-driven Biofoundry platform. This platform enables rapid discovery, design, and scaling of bio-based ingredients, demonstrating how artificial intelligence can accelerate innovation in biotechnology and personal care.
Together, Syensqo and Bota Biosciences are unlocking new possibilities in the hair and scalp care segment. Supported by Syensqo’s Renewable Materials & Biotechnology platform, the partnership is paving the way for more sustainable, high-performance ingredients that align with evolving consumer expectations. This launch not only reinforces their collaborative strength but also signals a broader transformation in the industry, where science, sustainability, and advanced technology converge to shape the future of personal care.
